News - Queen's Center for Biomedical Research

Congratulations to Dr. Michael A. Ortega for being awarded an R21 grant through the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health (NIH)! Dr. Ortega’s lab is based out of the Queen’s Medical Center for Biomedical Research (QCBR), where his team investigates mechanisms of kidney injury response.

August 29, 2023

The grant titled “TWEAK-Fn14 regulation of non-canonical NF-κB signaling in chronic renal inflammation,” will support the Ortega Lab for 3 years as the team focuses determining the role of non-canonical NF-κB signaling in promoting chronic cytokine pressure in response to kidney injury. Identifying proinflammatory features of

Congratulations to Dr. Michael A. Ortega for being awarded an R21 grant through the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health (NIH)! Dr. Ortega’s lab is based out of the Queen’s Medical Center for Biomedical Research (QCBR), where his team investigates mechanisms of kidney injury response.

The grant titled “TWEAK-Fn14 regulation of non-canonical NF-κB signaling in chronic renal inflammation,” will support the Ortega Lab for 3 years as the team focuses

August 29, 2023

It is always difficult to say goodbye to a valued team member and we are sad to see Brandon Johnson, PhD leave our department to face new challenges.

Brandon joined the Center for Biomedical Research in 2019 as Postdoctoral Fellow. He quickly advanced to Scientist, thanks to his rich experience in biophysics, calcium

August 11, 2023

Dr. Andrea Fleig and collaborators provide evidence that the TRPM7 protein is a promising target for epilepsy medication. The manuscript has been published in Epilepsia Open.

Conditions associated with low serum magnesium in humans (hypomagnesemia) can lead to seizures. The channel kinase TRPM7 is the most prominent protein in mammals that

June 16, 2023

Dr. Christine Peinelt is spending a 3-month sabbatical at QCBR

The Queen’s Center for Biomedical Research is hosting Dr. Christine Peinelt during her sabbatical leave of absence from her position as Professor and Principal Investigator

May 16, 2023

Dr. Sayuri Suzuki and colleagues show that the cannabinoid CBGA can ameliorate acute and chronic kidney disease. The manuscript has been published in Scientific Reports.

Dr. Suzuki’s study demonstrates that CBGA, and to a lesser extent CBD, can protect the kidney from damage that can arise acutely as a side-effect

April 14, 2023

Dr. Andrea Fleig and a Multi-Disciplinary Team Receive NIH IGNITE Grant to Develop New Drug

Dr. Fleig and her multi-disciplinary collaborative team were awarded a multi-year NIH grant through the NINDS IGNITE program. IGNITE stands for “Innovation Grants to Nurture

February 4, 2023

Dr. Michael Ortega and colleagues show that exocyst inactivation in urothelial cells disrupts autophagy and activates non-canonical NF-κB signaling. This study has been published in the journal Disease Models & Mechanisms.

Dr. Ortega’s study investigates a unique Exoc5 conditional knockout mouse that develops obstruction of the urinary tract during embryo development. This blockage causes an accumulation

October 12, 2022

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