News - Queen's Center for Biomedical Research

Drs. Sayuri Suzuki, Andrea Fleig, and colleagues identify the bioactive sites on waixenicin A that inhibit the TRPM7 channel. The manuscript has been published in the Journal of Natural Products.

April 1, 2024

In this study, Drs. Suzuki and Fleig collaborated with a multi-disciplinary of chemists and physiologists to characterize the structure-activity relationships of waixenicin A, a xenicane diterpene from the Hawaiian coral Sarcothelia edmondsoni. Waixenicin A is a selective and potent inhibitor of the TRPM7 ion channel, which is

Drs. Sayuri Suzuki, Andrea Fleig, and colleagues identify the bioactive sites on waixenicin A that inhibit the TRPM7 channel. The manuscript has been published in the Journal of Natural Products.

In this study, Drs. Suzuki and Fleig collaborated with a multi-disciplinary of chemists and physiologists to characterize the structure-activity relationships of waixenicin A, a xenicane

April 1, 2024

Dr. Sayuri Suzuki and colleagues show that the cannabinoid CBGA can ameliorate acute and chronic kidney disease. The manuscript has been published in Scientific Reports.

Dr. Suzuki’s study demonstrates that CBGA, and to a lesser extent CBD, can protect the kidney from damage that can arise acutely as a side-effect

April 14, 2023

Dr. Andrea Fleig and a Multi-Disciplinary Team Receive NIH IGNITE Grant to Develop New Drug

Dr. Fleig and her multi-disciplinary collaborative team were awarded a multi-year NIH grant through the NINDS IGNITE program. IGNITE stands for “Innovation Grants to Nurture

February 4, 2023

Dr. Michael Ortega and colleagues show that exocyst inactivation in urothelial cells disrupts autophagy and activates non-canonical NF-κB signaling. This study has been published in the journal Disease Models & Mechanisms.

Dr. Ortega’s study investigates a unique Exoc5 conditional knockout mouse that develops obstruction of the urinary tract during embryo development. This blockage causes an accumulation

October 12, 2022

Dr. Malika Faouzi and colleagues show that minor cannabinoids may be responsible for the anti-inflammatory and analgesic effects of Cannabis. This study has been published in the journal Function.

Dr. Faouzi’s study reports for the first time that several minor cannabinoids, mainly the carboxylic acid derivatives and particularly cannabigerolic acid (CBGA), demonstrated high potency

July 8, 2022

Dr. Malika Faouzi Receives Poster Award at the Leading Emerging & Diverse Scientists to Success Nashville Summit

The LEADS Nashville Summit was organized by the University of Pittsburgh between March 23 and 25, 2022.

May 10, 2022

Dr. Reinhold Penner at the UH Manoa Staff and Faculty Awards Ceremony

Provost Bruno, Reinhold Penner, President Lassner, Regent Haning III

May 2, 2022

News - Media

Drs. Sayuri Suzuki, Andrea Fleig, and colleagues identify the bioactive sites on waixenicin A that inhibit the TRPM7 channel. The manuscript has been published in the Journal of Natural Products.

Drs. Sayuri Suzuki, Andrea Fleig, and colleagues identify the bioactive sites on waixenicin A that inhibit the TRPM7 channel. The manuscript has been published in the Journal of Natural Products.

Dr. Sayuri Suzuki and colleagues show that the cannabinoid CBGA can ameliorate acute and chronic kidney disease. The manuscript has been published in Scientific Reports.

Dr. Andrea Fleig and a Multi-Disciplinary Team Receive NIH IGNITE Grant to Develop New Drug

Dr. Michael Ortega and colleagues show that exocyst inactivation in urothelial cells disrupts autophagy and activates non-canonical NF-κB signaling. This study has been published in the journal Disease Models & Mechanisms.

Dr. Malika Faouzi and colleagues show that minor cannabinoids may be responsible for the anti-inflammatory and analgesic effects of Cannabis. This study has been published in the journal Function.

Dr. Malika Faouzi Receives Poster Award at the Leading Emerging & Diverse Scientists to Success Nashville Summit

Dr. Reinhold Penner at the UH Manoa Staff and Faculty Awards Ceremony

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