QCBR Publications

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Cannabigerolic Acid (CBGA) inhibits the TRPM7 ion channel through its kinase domain
Suzuki S, Wakano C, Monteilh-Zoller MK, Cullen AJ, Fleig A, Penner R
Function5(1):zqad069 (2023)
DOI: 10.1093/function/zqad069     PMID: 38162115     PMCID: PMC10757070
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Plasma galectin-3 is associated with decreased glomerular filtration rate in chronic HIV
Vares-Lum DL, Gangcuangco LMA, Park J, Manzano E, Ortega MA, Chow D, Shikuma C
HIV Research & Clinical Practicein press (2023)
DOI: 10.1080/25787489.2023.2261753     PMID: 37783570     PMCID: PMC10695702 (available on 2024-10-02)
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Drugs acting at TRPM7 channels inhibit seizure-like activity
Khalil A, Shekh-Ahmad T, Kovac S, Wykes RC, Horgen FD, Fleig A, Walker MC
Epilepsia Open4:12773 (2023)
DOI: 10.1002/epi4.12773     PMID: 37328275      PMCID: PMC10472385
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CBGA ameliorates inflammation and fibrosis in nephropathy
Suzuki S, Fleig A, Penner R
Scientific Reports13(1):6341 (2023)
DOI: 10.1038/s41598-023-33507-2     PMID: 37072467     PMCID: PMC10113213
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Hypoxia-induced neurite outgrowth involves regulation through TRPM7
Turlova E, Ji D, Deurloo M, Wong R, Fleig A, Horgen FD, Sun HS, Feng ZP
Molecular Neurobiology 60:836-850 (2023)
DOI: 101007/s12035-022-03114-9     PMID: 36378470
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Exocyst inactivation in urothelial cells disrupts autophagy and activates non-canonical NF-κB
Ortega MA, Villiger RK, Harrison-Chau M, Lieu S, Tamashiro K-K, Lee AJ, Fujimoto BA, Patwardhan GY, Kepler J, Fogelgren B
Disease Models and Mechanisms 15 (10):dmm049785 (2022)
DOI: 10.1242/dmm.049785     PMID: 36004645     PMCID: PMC9586569
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Acidic cannabinoids suppress pro-inflammatory cytokine release by blocking Store-Operated Calcium Entry
Faouzi M, Wakano C, Monteilh-Zoller MK, Neupane RP, Starkus JG, Neupane JB, Cullen AJ, Johnson BE, Fleig A, Penner R
Function 3(4):zqac033 (2022)
DOI: 101093/function/zqac033     PMID: 35910331     PMCID: PMC9334010
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Sex-dependent effect of aging on calcium signaling and expression of TRPM2 and CRAC channels in human neutrophils
Vázquez-Prieto M, Lascurais-Santamaria N, Fernández-Eufrasio NB, Montiel-Condado D, Garibay-Escobar A, Patiño-López G, Penner R, Sumoza-Toledo A
Human Immunology 83(8-9):645-655 (2022)
DOI: 10.1016/j.humimm.2022.05.002     PMID: 35660323
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Interferon gamma upregulates the cytokine receptors IFNGR1 and TNFRSF1A in HT-29-MTX E12 cells
Johnson BE, Panek P, Yu A, Fischer E, Koba M, Mendoza Hermosillo D, Capaldo CT
Cytokine 156:155892 (2022)
DOI: 101016/jcyto2022155892     PMID: 35653895     PMCID: PMC9636846/
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Spirovetivane- and Eudesmane-Type Sesquiterpenoids isolated from the culture media of two cyanobacterial strains
O’Donnell TJ, Luo Y, Yoshida WY, Suzuki S, Sun R, Williams PG
Journal of Natural Products 85(2):415-425 (2022)
DOI: 10.1021/acs.jnatprod.1c01014     PMID: 35142496
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Modulators of TRPM7 and its potential as a drug target for brain tumours
Ji D, Fleig A, Horgen FD, Feng ZP, Sun HS
Cell Calcium 101, 192521 (2022)
DOI: 10.1016/j.ceca.2021.102521     PMID: 34953296
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Real-time optical analysis of a colorimetric LAMP assay for SARS-CoV-2 in saliva with a handheld instrument improves accuracy compared with endpoint assessment
Diaz LM, Johnson BE, Jenkins DM
Journal of Biomolecular Techniques 32, 158-171 (2021)
DOI: 10.7171/jbt.21-3203-011     PMID: 35027873     PMCID: PMC8730521
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Transient Receptor Potential C 1/4/5 is a determinant of MTI-101 induced calcium influx and cell death in multiple myeloma
Elzamzamy OM, Johnson BE, Chen W-C, Hu G, Penner R, Hazlehurst LA
Cells 10, 1490 (2021)
DOI: 103390/cells10061490     PMID: 34199280     PMCID: PMC8231892
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Role of TRPM7 kinase in cancer
Meng S, Alanazi R, Ji D, Bandura J, Luo ZW, Fleig A, Feng ZP, Sun HS
Cell Calcium 96:102400 (2021)
DOI: 10.1016/j.ceca.2021.102400     PMID: 33784560
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Inhibition of TRPM7 with waixenicin A reduces glioblastoma cellular functions
Wong R, Gong H, Alanazi R, Bondoc A, Luck A, Sabha N, Horgen FD, Fleig A, Rutka JT, Feng ZP, Sun HS
Cell Calcium 92:102307 (2020)
DOI: 10.1016/j.ceca.2020.102307     PMID: 33080445
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Waixenicin A, a marine-derived TRPM7 inhibitor: a promising CNS drug lead
Sun HS, Horgen FD, Romo D, Hull KG, Kiledal SA, Fleig A, Feng ZP
Acta Pharmacologica Sinica 41(12):1519-1524 (2020)
DOI: 101038/s41401-020-00512-4     PMID: 32994545
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TRPM7 mediates neuronal cell death upstream of calcium/calmodulin-dependent protein kinase II and calcineurin mechanism in neonatal hypoxic-ischemic brain injury
Turlova E, Wong R, Xu B, Li F, Du L, Habbous S, Horgen FD, Fleig A Feng ZP, Sun HS
Translational Stroke Research 12(1):164-184 (2020)
DOI: 101007/s12975-020-00810-3     PMID: 32430797
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Divalent cation influx and calcium homeostasis in germinal vesicle mouse oocytes
Ardestani G, Mehregan A, Fleig A, Horgen FD, Carvacho I, Fissore RA
Cell Calcium 87, 102181 (2020)
DOI: 10.1016/j.ceca.2020.102181     PMID: 32097818     PMCID: PMC7153984
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TRPM7 contributes to progressive nephropathy
Suzuki S, Penner R, Fleig A
Scientific Reports 10, 2333 (2020)
DOI: 101038/s41598-020-59355-y     PMID: 32047249     PMCID: PMC7012919
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The role of TRPC1 in modulating cancer progression
Elzamzamy OM, Penner R, Hazlehurst LA
Cells 9, 388 (2020)
DOI: 103390/cells9020388     PMID: 32046188     PMCID: PMC7072717
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Ca2+ homeostasis and Cancer
Gautier M, Trebak M, Fleig A, Vandier C, Ouadid-Ahidouch H
Cell Calcium 84, 102084 (2019)
DOI: 10.1016/j.ceca.2019.102084     PMID: 31593838
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Ca2+ channels in Cancer
Gautier M, Trebak M, Fleig A, Vandier C, Ouadid-Ahidouch H
Cell Calcium 84, 102083 (2019)
DOI: 10.1016/j.ceca.2019.102083     PMID: 31606459
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Pharmacology of JNJ-28583113: A novel TRPM2 antagonist
Fourgeaud L, Dvorak C, Faouzi M, Starkus J, Sahdeo S, Wang Q, Lord B, Coate H, Taylor N, He Y, Qin N, Wickenden A, Carruthers N, Lovenberg TW, Penner R, Bhattacharya A
European Journal of Pharmacology 853, 299-307 (2019)
DOI: 10.1016/j.ejphar.2019.03.043     PMID: 30965058
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Areca nut extracts mobilize calcium and release pro-inflammatory cytokines from various immune cells<
Faouzi M, Neupane RP, Yang J, Williams P, Penner R
Scientific Reports 8(1), 1075 (2018)
DOI: 101038/s41598-017-18996-2     PMID: 29348572     PMCID: PMC5773534
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TRPM7 channels play a role in high glucose-induced endoplasmic reticulum stress and neuronal cell apoptosis
Huang Y, Leng T-D, Inoue K, Yang T, Liu M, Horgen FD, Fleig A, Li J, Xiong Z-G
The Journal of Biological Chemistry 293(37), 14393-14406 (2018)
DOI: 10.1074/jbc.RA117.001032     PMID: 30076216     PMCID: PMC6139551
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The TRPM7 kinase limits receptor-induced calcium release by regulating heterotrimeric G-proteins
Suzuki S, Lis A, Schmitz C, Penner R, Fleig A
Cellular and Molecular Life Sciences: CMLS 75(16), 3069-3078 (2018)
DOI: 101007/s00018-018-2786-z     PMID: 29500477     PMCID: PMC6033657
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The TRPM7 channel kinase regulates store-operated calcium entry
Faouzi M, Kilch T, Horgen FD, Fleig A, Penner R
The Journal of Physiology 595(10), 3165-3180 (2017)
DOI: 101113/JP274006     PMID: 28130783     PMCID: PMC5430208
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New insights into Ca2+ channel function in health and disease
Fleig A, Parekh AB
The Journal of Physiology 595(10), 2997-2998 (2017)
DOI: 101113/JP274289     PMID: 28503825     PMCID: PMC5430230
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Inhibition of TRPM7 suppresses cell proliferation of colon adenocarcinoma in vitro and induces hypomagnesemia in vivo without affecting azoxymethane-induced early colon cancer in mice
Huang J, Furuya H, Faouzi M, Zhang Z, Monteilh-Zoller M, Kawabata KG, Horgen FD, Kawamori T, Penner R, Fleig A
Cell Communication and Signaling: CCS 15(1), 30 (2017)
DOI: 101186/s12964-017-0187-9     PMID: 28810912     PMCID: PMC5558780
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Plasmodium falciparum ligand binding to erythrocytes induce alterations in deformability essential for invasion
Sisquella X, Nebl T, Thompson JK, Whitehead L, Malpede BM, Salinas ND, Rogers K, Tolia NH, Fleig A, O’Neill J, Tham W-H, Horgen, FD, Cowman AF
ELife 6:e21083 (2017)
DOI: 10.7554/eLife.21083     PMID: 28226242     PMCID: PMC5333951
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Scalaradial Is a potent inhibitor of Transient Receptor Potential Melastatin 2 (TRPM2) ion channels
Starkus JG, Poerzgen P, Layugan K, Kawabata KG, Goto J-I, Suzuki S, Myers G, Kelly M, Penner R, Fleig A, Horgen FD
Journal of Natural Products 80(10), 2741-2750 (2017)
DOI: 10.1021/acs.jnatprod.7b00515     PMID: 29019677     PMCID: PMC6687308
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The coiled-coil domain of zebrafish TRPM7 regulates Mg·nucleotide sensitivity
Jansen C, Sahni J, Suzuki S, Horgen FD, Penner R, Fleig A
Scientific Reports 6, 33459 (2016)
DOI: 101038/srep33459     PMID: 27628598     PMCID: PMC5024298
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Human CNNM2 is not a Mg2+ transporter per se
Sponder G, Mastrototaro L, Kurth K, Merolle L, Zhang Z, Abdulhanan N, Smorodchenko A, Wolf K, Fleig A, Penner R, Iotti S, Aschenbach JR, Vormann J, Kolisek M
Pflugers Archiv: European Journal of Physiology 468(7), 1223-1240 (2016)
DOI: 101007/s00424-016-1816-7     PMID: 27068403
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TRPM7 regulates axonal outgrowth and maturation of primary hippocampal neurons
Turlova E, Bae C YJ, Deurloo M, Chen W, Barszczyk A, Horgen FD, Fleig A, Feng Z-P, Sun H-S
Molecular Neurobiology 53(1), 595-610 (2016)
DOI: 101007/s12035-014-9032-y     PMID: 25502295     PMCID: PMC4820394
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TRPM7 kinase activity regulates murine mast cell degranulation
Zierler S, Sumoza-Toledo A, Suzuki S, Dúill FÓ, Ryazanova LV, Penner R, Ryazanov AG, Fleig A
The Journal of Physiology 594(11), 2957-2970 (2016)
DOI: 101113/JP271564     PMID: 26660477     PMCID: PMC4887679
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State-dependent blocking mechanism of Kv13 channels by the antimycobacterial drug clofazimine
Faouzi M, Starkus JG, Penner R
British Journal of Pharmacology 172(21), 5161-5173 (2015)
DOI: 10.1111/bph.13283     PMID: 26276903     PMCID: PMC4687807
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Small-conductance Ca2+-activated potassium type 2 channels regulate the formation of contextual fear memory
Murthy SRK, Sherrin T, Jansen C, Nijholt I, Robles M, Dolga AM, Andreotti N, Sabatier J-M, Knaus H-G, Penner R, Todorovic C, Blank T
PloS One 10(5), e0127264 (2015)
DOI: 10.1371/journal.pone.0127264     PMID: 25938421     PMCID: PMC4418695
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Regulation of endogenous and heterologous Ca2+ release-activated Ca2+ currents by pH
Beck A, Fleig A, Penner R, Peinelt C
Cell Calcium 56(3), 235-243 (2014)
DOI: 10.1016/j.ceca.2014.07.011     PMID: 25168908     PMCID: PMC4162834
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Faouzi M, Penner R
Handbook of Experimental Pharmacology 222, 403-426 (2014)
DOI: 101007/978-3-642-54215-2_16     PMID: 24756715
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Fleig A, Chubanov V
Handbook of Experimental Pharmacology 222, 521-546 (2014)
DOI: 101007/978-3-642-54215-2_21     PMID: 24756720     PMCID: PMC5663634
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Elucidating the role of the TRPM7 alpha-kinase: TRPM7 kinase inactivation leads to magnesium deprivation resistance phenotype in mice
Ryazanova LV, Hu Z, Suzuki S, Chubanov V, Fleig A, Ryazanov AG
Scientific Reports 4, 7599 (2014)
DOI: 101038/srep07599     PMID: 25534891     PMCID: PMC4274504
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N-Myc-induced up-regulation of TRPM6/TRPM7 channels promotes neuroblastoma cell proliferation
Zhang Z, Faouzi M, Huang J, Geerts D, Yu H, Fleig A, Penner R
Oncotarget 5(17), 7625-7634 (2014)
DOI: 10.18632/oncotarget.2283     PMID: 25277194     PMCID: PMC4202149
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The TRPM6 kinase domain determines the Mg·ATP sensitivity of TRPM7/M6 heteromeric ion channels
Zhang Z, Yu H, Huang J, Faouzi M, Schmitz C, Penner R, Fleig, A
The Journal of Biological Chemistry 289(8), 5217-5227 (2014)
DOI: 10.1074/jbc.M113.512285     PMID: 24385424     PMCID: PMC3931078
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ORAI3 silencing alters cell proliferation and cell cycle progression via c-myc pathway in breast cancer cells
Faouzi M, Kischel P, Hague F, Ahidouch A, Benzerdjeb N, Sevestre H, Penner R, Ouadid-Ahidouch H
Biochimica et Biophysica Acta 1833(3), 752-760 (2013)
DOI: 10.1016/j.bbamcr.2012.12.009     PMID: 23266555
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Solute Carrier Family SLC41, what do we really know about it?
Fleig A, Schweigel-Röntgen M, Kolisek M
Wiley Interdisciplinary Reviews Membrane Transport and Signaling 2(6) (2013)
DOI: 10.1002/wmts.95     PMID: 24340240     PMCID: PMC3855994
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TRPM2 channels are not required for acute airway inflammation in OVA-induced severe allergic asthma in mice
Sumoza-Toledo A, Fleig A, Penner R
Journal of Inflammation (London, England) 10(1), 19 (2013)
DOI: 101186/1476-9255-10-19     PMID: 23631390     PMCID: PMC3648402
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STIM2 drives Ca2+ oscillations through store-operated Ca2+ entry caused by mild store depletion
Thiel M, Lis A, Penner R
The Journal of Physiology 591(Pt 6), 1433-1445 (2013)
DOI: 10.1113/jphysiol.2012.245399     PMID: 23359669     PMCID: PMC3607164
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TRPM7 triggers Ca2+ sparks and invadosome formation in neuroblastoma cells
Visser D, Langeslag M, Kedziora KM, Klarenbeek J, Kamermans A, Horgen FD, Fleig A, van Leeuwen FN, Jalink K
Cell Calcium 54(6), 404-415 (2013)
DOI: 10.1016/j.ceca.2013.09.003     PMID: 24176224     PMCID: PMC4912378
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TRPM7 is regulated by halides through its kinase domain
Yu H, Zhang Z, Lis A, Penner R, Fleig A
Cellular and Molecular Life Sciences: CMLS 70(15):2757-2771 (2013)
DOI: 101007/s00018-013-1284-6     PMID: 23471296     PMCID: PMC3710292
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Stimulation of Ca2+ channel Orai1/STIM1 by serum- and glucocorticoid-inducible kinase 1 (SGK1)
Eylenstein A, Gehring E-M, Heise N, Shumilina E, Schmidt S, Szteyn K, Münzer P, Nurbaeva MK, Eichenmüller M, Tyan L, Regel I, Föller, M, Kuhl D, Soboloff J, Penner R, Lang F
The FASEB Journal 25(6), 2012-2021 (2011)
DOI: 10.1096/fj.10-178210     PMID: 21385992     PMCID: PMC3999400
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Dendritic cell maturation and chemotaxis is regulated by TRPM2-mediated lysosomal Ca2+ release
Sumoza-Toledo A, Lange I, Cortado H, Bhagat H, Mori Y, Fleig A, Penner R, Partida-Sánchez S
The FASEB Journal 25(10), 3529-3542 (2011)
DOI: 10.1096/fj.10-178483     PMID: 21753080     PMCID: PMC3177582
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TRPM2: A multifunctional ion channel for calcium signaling
Sumoza-Toledo A, Penner R
The Journal of Physiology 589(Pt 7), 1515-1525 (2011)
DOI: 10.1113/jphysiol.2010.201855     PMID: 21135052     PMCID: PMC3099011
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Waixenicin A inhibits cell proliferation through magnesium-dependent block of Transient Receptor Potential Melastatin 7 (TRPM7) channels
Zierler S, Yao G, Zhang Z, Kuo WC, Pörzgen P, Penner R, Horgen FD, Fleig A
The Journal of Biological Chemistry 286(45), 39328-39335 (2011)
DOI: 10.1074/jbc.M111.264341     PMID: 21926172     PMCID: PMC3234757
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TRPM5 regulates glucose-stimulated insulin secretion
Brixel LR, Monteilh-Zoller MK, Ingenbrandt CS, Fleig A, Penner R, Enklaar T, Zabel BU, Prawitt D
Pflügers Archiv: European Journal of Physiology 460(1), 69-76 (2010)
DOI: 101007/s00424-010-0835-z     PMID: 20393858     PMCID: PMC5663632
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Development and optimization of a high-throughput bioassay for TRPM7 ion channel inhibitors
Castillo B, Pörzgen P, Penner R, Horgen FD, Fleig A
Journal of Biomolecular Screening 15(5), 498-507 (2010)
DOI: 101177/1087057110368294     PMID: 20413646     PMCID: PMC4725312
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Two novel 2-aminoethyl diphenylborinate (2-APB) analogues differentially activate and inhibit store-operated Ca2+ entry via STIM proteins
Goto J-I, Suzuki AZ, Ozaki S, Matsumoto N, Nakamura T, Ebisui E, Fleig A, Penner R, Mikoshiba K
Cell Calcium 47(1), 1-10 (2010)
DOI: 10.1016/j.ceca.2009.10.004     PMID: 19945161     PMCID: PMC2905153
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Activation of store-operated ICRAC by hydrogen peroxide
Grupe M, Myers G, Penner R, Fleig A
Cell Calcium 48(1), 1-9 (2010)
DOI: 101016/jceca201005005     PMID: 20646759     PMCID: PMC2929316
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A single lysine in the N-terminal region of store-operated channels is critical for STIM1-mediated gating
Lis A, Zierler S, Peinelt C, Fleig A, Penner R
The Journal of General Physiology 136(6), 673-686 (2010)
DOI: 10.1085/jgp.201010484     PMID: 21115697     PMCID: PMC2995155
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TRPM7 is essential for Mg2+ homeostasis in mammals
Ryazanova LV, Rondon LJ, Zierler S, Hu Z, Galli J, Yamaguchi TP, Mazur A, Fleig A, Ryazanov AG
Nature Communications 1, 109 (2010)
DOI: 101038/ncomms1108     PMID: 21045827     PMCID: PMC3060619
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The calcium-permeable non-selective cation channel TRPM2 is modulated by cellular acidification
Starkus JG, Fleig A, Penner R
The Journal of Physiology 588(Pt 8), 1227-1240 (2010)
DOI: 10.1113/jphysiol.2010.187476     PMID: 20194125     PMCID: PMC2872729
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TRPM2 functions as a lysosomal Ca2+-release channel in beta cells
Lange I, Yamamoto S, Partida-Sanchez S, Mori Y, Fleig A, Penner R
Science Signaling 2(71), ra23 (2009)
DOI: 10.1126/scisignal.2000278     PMID: 19454650     PMCID: PMC2779714
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IP3 receptor subtype-dependent activation of store-operated calcium entry through ICRAC
Peinelt C, Beck A, Monteilh-Zoller MK, Penner R, Fleig A
Cell Calcium 45(4), 326-330 (2009)
DOI: 10.1016/j.ceca.2008.12.001     PMID: 19157540     PMCID: PMC2744131
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Lipopolysaccharide-induced down-regulation of Ca2+ release-activated Ca2+ currents (ICRAC) but not Ca2+-activated TRPM4-like currents (ICAN) in cultured mouse microglial cells
Beck A, Penner R, Fleig A
The Journal of Physiology 586(2), 427-439 (2008)
DOI: 10.1113/jphysiol.2007.145151     PMID: 17991695     PMCID: PMC2375604
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SLC41A1 is a novel mammalian Mg2+ carrier
Kolisek M, Launay P, Beck A, Sponder G, Serafini N, Brenkus M, Froschauer EM, Martens H, Fleig A, Schweigel M
The Journal of Biological Chemistry 283(23), 16235-16247 (2008)
DOI: 10.1074/jbc.M707276200     PMID: 18367447     PMCID: PMC2414286
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Synergistic regulation of endogenous TRPM2 channels by adenine dinucleotides in primary human neutrophils
Lange I, Penner R, Fleig A, Beck A
Cell Calcium 44(6), 604-615 (2008)
DOI: 10.1016/j.ceca.2008.05.001     PMID: 18572241     PMCID: PMC2597220
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STIM2 protein mediates distinct store-dependent and store-independent modes of CRAC channel activation
Parvez S, Beck A, Peinelt C, Soboloff J, Lis A, Monteilh-Zoller M, Gill DL, Fleig A, Penner R
The FASEB Journal 22(3), 752-761 (2008)
DOI: 10.1096/fj.07-9449com     PMID: 17905723     PMCID: PMC3601890
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2-Aminoethoxydiphenyl borate directly facilitates and indirectly inhibits STIM1-dependent gating of CRAC channels
Peinelt C, Lis A, Beck A, Fleig A, Penner R
The Journal of Physiology 586(13), 3061-3073 (2008)
DOI: 10.1113/jphysiol.2008.151365     PMID: 18403424     PMCID: PMC2538778
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Clofazimine inhibits human Kv13 potassium channel by perturbing calcium oscillation in T lymphocytes
Ren YR, Pan F, Parvez S, Fleig A, Chong CR, Xu J, Dang Y, Zhang J, Jiang H, Penner R, Liu JO
PloS One 3(12), e4009 (2008)
DOI: 10.1371/journal.pone.0004009     PMID: 19104661     PMCID: PMC2602975
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TRPM2-mediated Ca2+ influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration
Yamamoto S, Shimizu S, Kiyonaka S, Takahashi N, Wajima T, Hara Y, Negoro T, Hiroi T, Kiuchi Y, Okada T, Kaneko S, Lange I, Fleig A, Penner R, Nishi M, Takeshima H, Mori Y
Nature Medicine 14(7), 738-747 (2008)
DOI: 101038/nm1758     PMID: 18542050     PMCID: PMC2789807
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TRPM7 channel is sensitive to osmotic gradients in human kidney cells
Bessac BF, Fleig, A
The Journal of Physiology 582(Pt 3), 1073-1086 (2007)
DOI: 10.1113/jphysiol.2007.130534     PMID: 17510191     PMCID: PMC2075261
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TRPM4 controls insulin secretion in pancreatic β-cells
Cheng H, Beck A, Launay P, Gross SA, Stokes AJ, Kinet J-P, Fleig A, Penner R
Cell Calcium 41(1), 51-61 (2007)
DOI: 10.1016/j.ceca.2006.04.032     PMID: 16806463     PMCID: PMC5663640
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CRACM1, CRACM2, and CRACM3 are store-operated Ca2+ channels with distinct functional properties
Lis A, Peinelt C, Beck A, Parvez S, Monteilh-Zoller M, Fleig A, Penner R
Current Biology 17(9), 794-800 (2007)
DOI: 10.1016/j.cub.2007.03.065     PMID: 17442569     PMCID: PMC5663639
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The Mg2+ and Mg2+-nucleotide-regulated channel-kinase TRPM7
Penner R, Fleig A
Handbook of Experimental Pharmacology 179(179), 313-328 (2007)
DOI: 101007/978-3-540-34891-7_19     PMID: 17217066     PMCID: PMC5663631
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Regulation of TRPM2 by extra- and intracellular calcium
Starkus JG, Beck A, Fleig A, Penner R
The Journal of General Physiology 130(4), 427-440 (2007)
DOI: 10.1085/jgp.200709836     PMID: 17893195     PMCID: PMC2151648
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Cell cycle-dependent regulation of store-operated ICRAC and Mg2+-nucleotide-regulated MagNuM (TRPM7) currents
Tani D, Monteilh-Zoller MK, Fleig A, Penner R
Cell Calcium 41(3), 249-260 (2007)
DOI: 10.1016/j.ceca.2006.07.004     PMID: 17064762     PMCID: PMC5663638
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Nicotinic acid adenine dinucleotide phosphate and cyclic ADP-ribose regulate TRPM2 channels in T lymphocytes
Beck A, Kolisek M, Bagley LA, Fleig A, Penner R
The FASEB Journal 20(7), 962-964 (2006)
DOI: 10.1096/fj.05-5538fje     PMID: 16585058
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TRPM7 channel is regulated by magnesium nucleotides via its kinase domain
Demeuse P, Penner R, Fleig A
The Journal of General Physiology 127(4), 421-434 (2006)
DOI: 10.1085/jgp.200509410     PMID: 16533898     PMCID: PMC2151514
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Amplification of CRAC current by STIM1 and CRACM1 (Orai1)
Peinelt C, Vig M, Koomoa DL, Beck A, Nadler MJS, Koblan-Huberson M, Lis A, Fleig A, Penner R, Kinet J-P
Nature Cell Biology 8(7), 771-773 (2006)
DOI: 101038/ncb1435     PMID: 16733527     PMCID: PMC5685802
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TRPA1 is a substrate for de-ubiquitination by the tumor suppressor CYLD
Stokes AJ, Wakano C, Koblan-Huberson M, Adra CN, Fleig A, Turner HC
Cellular Signalling 18(10), 1584-1594 (2006)
DOI: 10.1016/j.cellsig.2005.12.009     PMID: 16500080
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A pyrazole derivative potently inhibits lymphocyte Ca2+ influx and cytokine production by facilitating transient receptor potential melastatin 4 channel activity
Takezawa R, Cheng H, Beck A, Ishikawa J, Launay P, Kubota H, Kinet J-P, Fleig A, Yamada T, Penner R
Molecular Pharmacology 69(4), 1413-1420 (2006)
DOI: 10.1124/mol.105.021154     PMID: 16407466
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CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry
Vig M, Peinelt C, Beck A, Koomoa DL, Rabah D, Koblan-Huberson M, Kraft S, Turner HC, Fleig A, Penner R, & Kinet J-P
Science 312(5777), 1220-1223 (2006)
DOI: 10.1126/science.1127883     PMID: 16645049     PMCID: PMC5685805
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CRACM1 multimers form the ion-selective pore of the CRAC channel
Vig M, Beck A, Billingsley JM, Lis A, Parvez S, Peinelt C, Koomoa DL, Soboloff J, Gill DL, Fleig A, Kinet J-P, Penner, R
Current Biology 16(20), 2073-2079 (2006)
DOI: 10.1016/j.cub.2006.08.085     PMID: 16978865     PMCID: PMC5685803
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Cyclic ADP-ribose and hydrogen peroxide synergize with ADP-ribose in the activation of TRPM2 channels
Kolisek M, Beck A, Fleig A, Penner R
Molecular Cell 18(1), 61-69 (2005)
DOI: 10.1016/j.molcel.2005.02.033     PMID: 15808509
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Emerging roles of TRPM channels
Fleig A, Penner R
Novartis Foundation Symposium 258, 248-258; discussion 258-266 (2004)
PMID: 15104187
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The TRPM ion channel subfamily: Molecular, biophysical and functional features
Fleig A, Penner R
Trends in Pharmacological Sciences 25(12), 633-639 (2004)
DOI: 10.1016/     PMID: 15530641
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D-6-Deoxy-myo-inositol 1,3,4,5-tetrakisphosphate, a mimic of d-myo-inositol 1,3,4,5-tetrakisphosphate: Biological activity and pH-dependent conformational properties
Horne G, Maechling C, Fleig A, Hirata M, Penner R, Spiess B, Potter BVL
Biochemical and Biophysical Research Communications 320(4), 1262-1270 (2004)
DOI: 10.1016/j.bbrc.2004.06.079     PMID: 15249226
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TRPM4 regulates calcium oscillations after T cell activation
Launay P, Cheng H, Srivatsan S, Penner R, Fleig A, Kinet J-P
Science 306(5700), 1374-1377 (2004)
DOI: 10.1126/science.1098845     PMID: 15550671
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Store-operated calcium entry: A tough nut to CRAC
Penner R, Fleig A
Science’s STKE: Signal Transduction Knowledge Environment 2004(243), pe38 (2004)
DOI: 10.1126/stke.2432004pe38     PMID: 15280580
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Dual-function ion channel/protein kinases: Novel components of vertebrate magnesium regulatory mechanisms
Schmitz C, Perraud A-L, Fleig A, Scharenberg AM
Pediatric Research 55(5), 734-737 (2004)
DOI: 10.1203/01.PDR.0000117848.37520.A2     PMID: 14764909
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Receptor-mediated regulation of the TRPM7 channel through its endogenous protein kinase domain
Takezawa R, Schmitz C, Demeuse P, Scharenberg AM, Penner R, Fleig A
Proceedings of the National Academy of Sciences of the United States of America 101(16), 6009-6014 (2004)
DOI: 10.1073/pnas.0307565101     PMID: 15069188     PMCID: PMC395914
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TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions
Monteilh-Zoller MK, Hermosura MC, Nadler MJS, Scharenberg AM, Penner R, Fleig A
The Journal of General Physiology 121(1), 49-60 (2003)
DOI: 10.1085/jgp.20028740     PMID: 12508053     PMCID: PMC2217320
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TRPM5 is a transient Ca2+-activated cation channel responding to rapid changes in [Ca2+]i
Prawitt D, Monteilh-Zoller MK, Brixel L, Spangenberg C, Zabel B, Fleig A, Penner R
Proceedings of the National Academy of Sciences of the United States of America 100(25), 15166-15171 (2003)
DOI: 10.1073/pnas.2334624100     PMID: 14634208     PMCID: PMC299937
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Regulation of vertebrate cellular Mg2+ homeostasis by TRPM7
Schmitz C, Perraud A-L, Johnson C O, Inabe K, Smith MK, Penner R, Kurosaki T, Fleig A, Scharenberg AM
Cell 114(2), 191-200 (2003)
DOI: 101016/s0092-8674(03)00556-7     PMID: 12887921
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Discrimination of intracellular calcium store subcompartments using TRPV1 (Transient Receptor Potential Channel, Vanilloid subfamily member 1) release channel activity
Turner HC, Fleig A, Stokes AJ, Kinet J-P, Penner R
The Biochemical Journal 371(Pt 2), 341-350 (2003)
DOI: 101042/BJ20021381     PMID: 12513687     PMCID: PMC1223279
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Dissociation of the store-operated calcium current ICRAC and the Mg-nucleotide-regulated metal ion current MagNuM
Hermosura MC, Monteilh-Zoller MK, Scharenberg AM, Penner R, Fleig A
The Journal of Physiology 539(Pt 2), 445-458 (2002)
DOI: 10.1113/jphysiol.2001.013361     PMID: 11882677     PMCID: PMC2290162
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TRPM4 is a Ca2+-activated nonselective cation channel mediating cell membrane depolarization
Launay P, Fleig A, Perraud AL, Scharenberg AM, Penner R, Kinet J P
Cell 109(3), 397-407 (2002)
DOI: 101016/s0092-8674(02)00719-5     PMID: 12015988
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A unified nomenclature for the superfamily of TRP cation channels
Montell C, Birnbaumer L, Flockerzi V, Bindels RJ, Bruford EA, Caterina MJ, Clapham DE, Harteneck C, Heller S, Julius D, Kojima I, Mori Y, Penner R, Prawitt D, Scharenberg AM, Schultz G, Shimizu N, Zhu MX
Molecular Cell 9(2), 229-231 (2002)
DOI: 101016/S1097-2765(02)00448-3     PMID: 11864597
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Transient receptor potential 1 regulates capacitative Ca2+ entry and Ca2+ release from endoplasmic reticulum in B lymphocytes
Mori Y, Wakamori M, Miyakawa T, Hermosura M, Hara Y, Nishida M, Hirose K, Mizushima A, Kurosaki M, Mori E, Gotoh K, Okada T, Fleig A, Penner R, Iino M, Kurosaki T
The Journal of Experimental Medicine 195(6), 673-681 (2002)
DOI: 10.1084/jem.20011758     PMID: 11901194     PMCID: PMC2193746
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LTRPC7 is a Mg·ATP-regulated divalent cation channel required for cell viability
Nadler MJS, Hermosura MC, Inabe K, Perraud A-L, Zhu Q, Stokes AJ, Kurosaki T, Kinet J-P, Penner R, Scharenberg AM, Fleig, A
Nature 411(6837), 590-595 (2001)
DOI: 101038/35079092     PMID: 11385574
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ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology
Perraud A-L, Fleig A, Dunn CA, Bagley LA, Launay P, Schmitz C, Stokes AJ, Zhu Q, Bessman MJ, Penner R, Kinet J-P, Scharenberg AM
Nature 411(6837), 595-599 (2001)
DOI: 101038/35079100     PMID: 11385575
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CaT1 and the calcium release-activated calcium channel manifest distinct pore properties
Voets T, Prenen J, Fleig A, Vennekens R, Watanabe H, Hoenderop JG, Bindels RJ, Droogmans G, Penner R, Nilius B
The Journal of Biological Chemistry 276(51), 47767-47770 (2001)
DOI: 10.1074/jbc.C100607200     PMID: 11687570
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Hearing threshold and frequency discrimination in the purely aquatic frog Xenopus laevis (Pipidae): Measurement by means of conditioning
Elepfandt A, Eistetter I, Fleig A, Günther E, Hainich M, Hepperle S, Traub B
The Journal of Experimental Biology 203(Pt 23), 3621-3629 (2000)
DOI: 10.1242/jeb.203.23.3621     PMID: 11060223
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InsP4 facilitates store-operated calcium influx by inhibition of InsP3 5-phosphatase
Hermosura MC, Takeuchi H, Fleig A, Riley AM, Potter BV, Hirata M, Penner R
Nature 408(6813), 735-740 (2000)
DOI: 101038/35047115     PMID: 11130077

Previous Publications

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Differential modulation of voltage-dependent Ca2+ currents by EGTA and BAPTA in bovine adrenal chromaffin cells
Bödding M, Penner R
Pflugers Archiv: European Journal of Physiology 439(1-2), 27-38 (1999)
DOI: 101007/s004249900158     PMID: 10650997
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Calcium release-activated calcium current (ICRAC) is a direct target for sphingosine
Mathes C, Fleig A, Penner R
The Journal of Biological Chemistry 273(39), 25020-25030 (1998)
DOI: 10.1074/jbc.273.39.25020     PMID: 9737958
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Near-visible ultraviolet light induces a novel ubiquitous calcium-permeable cation current in mammalian cell lines
Mendez F, Penner R
The Journal of Physiology 507 ( Pt 2), 365-377 (1998)
DOI: 10.1111/j.1469-7793.1998.365bt.x     PMID: 9518699     PMCID: PMC2230791
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The store-operated calcium current ICRAC: Nonlinear activation by InsP3 and dissociation from calcium release
Parekh AB, Fleig A, Penner R
Cell 89(6), 973-980 (1997)
DOI: 101016/s0092-8674(00)80282-2     PMID: 9200615
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Effects of clamp rise-time on rat brain IIA sodium channels in Xenopus oocytes
Ruben PC, Fleig A, Featherstone D, Starkus JG, Rayner MD
Journal of Neuroscience Methods 73(2), 113-122 (1997)
DOI: 101016/s0165-0270(96)02216-9     PMID: 9196281
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Store depletion and calcium influx
Parekh AB, Penner R
Physiological Reviews 77(4), 901-930 (1997)
DOI: 10.1152/physrev.1997.77.4.901     PMID: 9354808
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Ca2+-induced Ca2+ release in Chinese hamster ovary (CHO) cells co-expressing dihydropyridine and ryanodine receptors
Suda N, Franzius D, Fleig A, Nishimura S, Bödding M, Hoth M, Takeshima H, Penner R
The Journal of General Physiology 109(5), 619-631 (1997)
DOI: 10.1085/jgp.109.5.619     PMID: 9154908     PMCID: PMC2217062
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Acceleration of membrane recycling by axotomy of cultured Aplysia neurons
Ashery U, Penner R, Spira ME
Neuron 16(3), 641-651 (1996)
DOI: 101016/s0896-6273(00)80083-5     PMID: 8785061
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Silent calcium channels generate excessive tail currents and facilitation of calcium currents in rat skeletal myoballs
Fleig A, Penner R
The Journal of Physiology 494 ( Pt 1), 141-153 (1996)
DOI: 10.1113/jphysiol.1996.sp021481     PMID: 8814612     PMCID: PMC1160620
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Absence of Ca2+ current facilitation in skeletal muscle of transgenic mice lacking the type 1 ryanodine receptor
Fleig A, Takeshima H, Penner R
The Journal of Physiology 496 ( Pt 2), 339-345 (1996)
DOI: 10.1113/jphysiol.1996.sp021689     PMID: 8910220     PMCID: PMC1160881
Regulation of store-operated calcium currents in mast cells
Parekh AB, Penner R
Society of General Physiologists Series 51, 231-239 (1996)
PMID: 8809947
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Characterization of the Ca2+ current in isolated terminals of crustacean peptidergic neurons
Richmond JE, Penner R, Keller R, Cooke IM
The Journal of Experimental Biology 199(Pt 9), 2053-2059 (1996)
DOI: 10.1242/jeb.199.9.2053     PMID: 8831146
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Excessive repolarization-dependent calcium currents induced by strong depolarizations in rat skeletal myoballs
Fleig A, Penner R
The Journal of Physiology 489 ( Pt 1), 41-53 (1995)
DOI: 10.1113/jphysiol.1995.sp021028     PMID: 8583414     PMCID: PMC1156790
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Activation of store-operated calcium influx at resting InsP3 levels by sensitization of the InsP3 receptor in rat basophilic leukaemia cells
Parekh AB, Penner R
The Journal of Physiology 489 ( Pt 2), 377-382 (1995)
DOI: 10.1113/jphysiol.1995.sp021058     PMID: 8847633     PMCID: PMC1156765
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Depletion-activated calcium current is inhibited by protein kinase in RBL-2H3 cells
Parekh AB, Penner R
Proceedings of the National Academy of Sciences of the United States of America 92(17), 7907-7911 (1995)
DOI: 10.1073/pnas.92.17.7907     PMID: 7644512     PMCID: PMC41255
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Non-specific effects of calcium entry antagonists in mast cells
Franzius D, Hoth M, Penner R
Pflugers Archiv: European Journal of Physiology 428(5-6), 433-438 (1994)
DOI: 101007/bf00374562     PMID: 7838664
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Mice sans synaptotagmin
Neher E, Penner R
Nature 372(6504), 316-317 (1994)
DOI: 101038/372316a0     PMID: 7969483
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Membrane repolarization stops caffeine-induced Ca2+ release in skeletal muscle cells
Suda N, Penner R
Proceedings of the National Academy of Sciences of the United States of America 91(12), 5725-5729 (1994)
DOI: 10.1073/pnas.91.12.5725     PMID: 8202554     PMCID: PMC44069
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Kinetic mode switch of rat brain IIA Na channels in Xenopus oocytes excised macropatches
Fleig A, Ruben PC, Rayner MD
Pflügers Archiv: European Journal of Physiology 427(5-6), 399-405 (1994)
DOI: 101007/bf00374253     PMID: 797113
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Point mutations in IIS4 alter activation and inactivation of rat brain IIA Na channels in Xenopus oocyte macropatches
Fleig A, Fitch JM, Goldin AL, Rayner MD, Starkus JG, Ruben PC
Pflügers Archiv: European Journal of Physiology 427(5-6), 406-413 (1994)
DOI: 101007/BF00374254     PMID: 7971139
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Fast and slow inactivation of sodium channels: Effects of photodynamic modification by methylene blue
Starkus JG, Rayner MD, Fleig A, Ruben PC
Biophysical Journal 65(2), 715-726 (1993)
DOI: 101016/S0006-3495(93)81098-1     PMID: 821889     PMCID: PMC1225774
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Ca2+ and Mn2+ influx through receptor-mediated activation of nonspecific cation channels in mast cells
Fasolato C, Hoth M, Matthews G, Penner R
Proceedings of the National Academy of Sciences of the United States of America 90(7), 3068-3072 (1993)
DOI: 10.1073/pnas.90.7.3068     PMID: 7681994     PMCID: PMC46238
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A GTP-dependent step in the activation mechanism of capacitative calcium influx
Fasolato C, Hoth M, Penner R
The Journal of Biological Chemistry 268(28), 20737-20740 (1993)
PMID: 8407897
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Multiple mechanisms of manganese-induced quenching of fura-2 fluorescence in rat mast cells
Fasolato C, Hoth M, Penner R
Pflugers Archiv: European Journal of Physiology 423(3-4), 225-231 (1993)
DOI: 101007/bf00374399     PMID: 8321625
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Ion channels and calcium signaling in mast cells
Hoth M, Fasolato C, Penner R
Annals of the New York Academy of Sciences 707, 198-209 (1993)
DOI: 10.1111/j.1749-6632.1993.tb38053.x     PMID: 9137553
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Calcium release-activated calcium current in rat mast cells
Hoth M, Penner R
The Journal of Physiology 465, 359-386 (1993)
DOI: 10.1113/jphysiol.1993.sp019681     PMID: 8229840     PMCID: PMC1175434
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Calcium influx and its control by calcium release
Penner R, Fasolato C, Hoth M
Current Opinion in Neurobiology 3(3), 368-374 (1993)
DOI: 101016/0959-4388(93)90130-q     PMID: 8396477
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Transfected cGMP-dependent protein kinase suppresses calcium transients by inhibition of inositol 1,4,5-trisphosphate production
Ruth P, Wang GX, Boekhoff I, May B, Pfeifer A, Penner R, Korth M, Breer H, Hofmann F
Proceedings of the National Academy of Sciences of the United States of America 90(7), 2623-2627 (1993)
DOI: 10.1073/pnas.90.7.2623     PMID: 8385340     PMCID: PMC46147
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Depletion of intracellular calcium stores activates a calcium current in mast cells
Hoth M, Penner R
Nature 355(6358), 353-356 (1992)
DOI: 101038/355353a0     PMID: 1309940
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Novel chloride conductance in the membrane of bovine chromaffin cells activated by intracellular GTP gamma S
Doroshenko P, Penner R, Neher, E
The Journal of Physiology 436, 711-724 (1991)
DOI: 10.1113/jphysiol.1991.sp018575     PMID: 1712041     PMCID: PMC1181530
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Guanosine 5’-[beta-thio]triphosphate selectively activates calcium signaling in mast cells
von zur Mühlen F, Eckstein F, Penner R
Proceedings of the National Academy of Sciences of the United States of America 88(3), 926-930 (1991)
DOI: 10.1073/pnas.88.3.926     PMID: 1992486     PMCID: PMC50927
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A GTP analogue induces calcium release but not secretion in rat mast cells
von zur Mühlen F, Penner R
International Archives of Allergy and Applied Immunology 94(1-4), 74-75 (1991)
DOI: 101159/000235329     PMID: 1657794
Effects of angiotensin II on intracellular calcium and electrical function of mouse renal juxtaglomerular cells
Kurtz A, Penner R
Kidney International Supplement 30, S51-54 (1990)
PMID: 2175372
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Lack of direct evidence for a functional role of voltage-operated calcium channels in juxtaglomerular cells
Kurtz A, Skott O, Chegini S, Penner R
Pflugers Archiv: European Journal of Physiology 416(3), 281-287 (1990)
DOI: 101007/bf00392064     PMID: 2166274
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Angiotensin II induces oscillations of intracellular calcium and blocks anomalous inward rectifying potassium current in mouse renal juxtaglomerular cells
Kurtz A, Penner R
Proceedings of the National Academy of Sciences of the United States of America 86(9), 3423-3427 (1989)
DOI: 10.1073/pnas.86.9.3423     PMID: 2541447     PMCID: PMC287145
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Second messenger-activated calcium influx in rat peritoneal mast cells
Matthews G, Neher E, Penner R
The Journal of Physiology 418, 105-130 (1989)
DOI: 10.1113/jphysiol.1989.sp017830     PMID: 2559968     PMCID: PMC1189961
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Chloride conductance activated by external agonists and internal messengers in rat peritoneal mast cells
Matthews G, Neher E, Penner R
The Journal of Physiology 418, 131-144 (1989)
DOI: 10.1113/jphysiol.1989.sp017831     PMID: 2559969     PMCID: PMC1189962
Stimulus-secretion coupling in mast cells
Penner R, Neher E
Society of General Physiologists Series 44, 295-310 (1989)
PMID: 2781355
[The importance of calcium for secretion in excitable and non-excitable cells]
Penner R, Neher E
Arzneimittel-Forschung 39(1A), 174-177 (1989)
PMID: 2655617
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Regulation of calcium influx by second messengers in rat mast cells
Penner R, Matthews G, Neher E
Nature 334(6182), 499-504 (1988)
DOI: 101038/334499a0     PMID: 2457169
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The role of calcium in stimulus-secretion coupling in excitable and non-excitable cells
Penner R, Neher E
The Journal of Experimental Biology 139, 329-345 (1988)
DOI: 10.1242/jeb.139.1.329     PMID: 2850338
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Secretory responses of rat peritoneal mast cells to high intracellular calcium
Penner R, Neher E
FEBS Letters 226(2), 307-313 (1988)
DOI: 101016/0014-5793(88)81445-5     PMID: 3123272
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Multiple signaling pathways control stimulus-secretion coupling in rat peritoneal mast cells
Penner R
Proceedings of the National Academy of Sciences of the United States of America 85(24), 9856-9860 (1988)
DOI: 10.1073/pnas.85.24.9856     PMID: 3059353     PMCID: PMC282880
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Functional expression of the calcium release channel from skeletal muscle ryanodine receptor cDNA
Penner R, Neher E, Takeshima H, Nishimura S, Numa S
FEBS Letters 259(1), 217-221 (1989)
DOI: 101016/0014-5793(89)81532-7     PMID: 2557244
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The patch-clamp technique in the study of secretion
Penner R, Neher E
Trends in Neurosciences 12(4), 159-163 (1989)
DOI: 101016/0166-2236(89)90059-3     PMID: 2470174
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Differential effects of various secretagogues on quantal transmitter release from mouse motor nerve terminals treated with botulinum A and tetanus toxin
Dreyer F, Rosenberg F, Becker C, Bigalke H, Penner R
Naunyn-Schmiedeberg’s Archives of Pharmacology 335(1), 1-7 (1987)
DOI: 101007/bf00165027     PMID: 2883583
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The actions of presynaptic snake toxins on membrane currents of mouse motor nerve terminals
Dreyer F, Penner R
The Journal of Physiology 386, 455-463 (1987)
DOI: 10.1113/jphysiol.1987.sp016544     PMID: 2445966     PMCID: PMC1192472
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Distinct sites of action of clostridial neurotoxins revealed by double-poisoning of mouse motor nerve terminals
Gansel M, Penner R, Dreyer F
Pflugers Archiv: European Journal of Physiology 409(4-5), 533-539 (1987)
DOI: 101007/bf00583812     PMID: 2888074
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Washout phenomena in dialyzed mast cells allow discrimination of different steps in stimulus-secretion coupling
Penner R, Pusch M, Neher E
Bioscience Reports 7(4), 313-321 (1987)
DOI: 101007/bf01121453     PMID: 2445392
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Two different presynaptic calcium currents in mouse motor nerve terminals
Penner R, Dreyer F
Pflugers Archiv: European Journal of Physiology 406(2), 190-197 (1986)
DOI: 101007/bf00586682     PMID: 2421238
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Intracellularly injected tetanus toxin inhibits exocytosis in bovine adrenal chromaffin cells
Penner R, Neher E, Dreyer F
Nature 324(6092), 76-78 (1986)
DOI: 101038/324076a0     PMID: 3785374
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Dendrotoxin: A selective blocker of a non-inactivating potassium current in guinea-pig dorsal root ganglion neurones
Penner,R, Petersen,M, Pierau FK, Dreyer F
Pflugers Archiv: European Journal of Physiology 407(4), 365-369 (1986)
DOI: 101007/bf00652619     PMID: 2430257
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Beta-bungarotoxin inhibits a non-inactivating potassium current in guinea pig dorsal root ganglion neurones
Petersen M, Penner R, Pierau FK, Dreyer F
Neuroscience Letters 68(1), 141-145 (1986)
DOI: 101016/0304-3940(86)90244-2     PMID: 2425306
Action of botulinum A toxin and tetanus toxin on synaptic transmission
Dreyer F, Becker C, Bigalke H, Funk J, Penner R, Rosenberg F, Ziegler M
Journal De Physiologie (Paris) 79(4), 252-258 (1984)
PMID: 6152293