Dr. Suzuki’s study demonstrates that CBGA, and to a lesser extent CBD, can protect the kidney from damage that can arise acutely as a side-effect of anti-cancer chemotherapy with cisplatin or chronically in obstructive nephropathy and renal fibrosis. The authors demonstrate that CBGA, but not CBD, has a potent inhibitory effect on the channel-kinase TRPM7. They conclude that cannabinoids possess kidney-protective properties, with CBGA having a higher efficacy that is likely due to its dual anti-fibrotic and anti-inflammatory effects paired with TRPM7 inhibition.