Dr. Michael Ortega and colleagues show that exocyst inactivation in urothelial cells disrupts autophagy and activates non-canonical NF-κB signaling. This study has been published in the journal Disease Models & Mechanisms.
Dr. Ortega’s study investigates a unique Exoc5 conditional knockout mouse that develops obstruction of the urinary tract during embryo development. This blockage causes an accumulation
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October 12, 2022
