QCBR
The Queen's Medical Center
  • QCBR
  • LCMS
  • HTS
  • News
  • Publications
  • Make a Gift
  • Gallery
  • iQCBR
  • COVID
  • US
  • Global

TRPM7 Channels Play A Role In High Glucose-Induced Endoplasmic Reticulum Stress And Neuronal Cell Apoptosis.

8/3/2018

 
Picture
Huang Y, Leng TD, Inoue K, Yang T, Liu M, Horgen FD, Fleig A, Li J, Xiong ZG.
J Biol Chem. 2018 Sep 14;293(37):14393-14406. doi: 10.1074/jbc.RA117.001032. Epub 2018 Aug 3. PMED ID: 30076216.

The TRPM7 kinase limits receptor-induced calcium release by regulating heterotrimeric G-proteins

3/2/2018

 
Picture
Suzuki S, Lis A, Schmitz C, Penner R, Fleig A. 
​
The TRPM7 kinase limits receptor-induced calcium release by regulating heterotrimeric G-proteins. Cell Mol Life Sci. 2018 Mar 2. doi: 10.1007/s00018-018-2786-z. PMED ID: 29500477.

Areca nut extracts mobilize calcium and release pro-inflammatory cytokines from various immune cells

1/18/2018

 
Picture
Faouzi M, Neupane RP, Yang J, Williams P, Penner R.
​
Areca nut extracts mobilize calcium and release pro-inflammatory cytokines from various immune cells. Sci Rep. 2018 Jan 18;8(1):1075. doi: 10.1038/s41598-017-18996-2. PMED ID: 29348572.

Scalaradial Is a Potent Inhibitor of Transient Receptor Potential Melastatin 2 (TRPM2) Ion Channels

10/11/2017

 
Picture
Starkus JG, Poerzgen P, Layugan K, Kawabata KG, Goto JI, Suzuki S, Myers G, Kelly M, Penner R, Fleig A, Horgen FD. 
​
Scalaradial Is a Potent Inhibitor of Transient Receptor Potential Melastatin 2 (TRPM2) Ion Channels. J Nat Prod. 2017 Oct 27;80(10):2741-2750. doi: 10.1021/acs.jnatprod.7b00515. Epub 2017 Oct 11. PMID: 29019677.

Inhibition of TRPM7 suppresses cell proliferation of colon adenocarcinoma in vitro and induces hypomagnesemia in vivo without affecting azoxymethane-induced early colon cancer in mice

8/15/2017

 
Picture
Huang J, Furuya H, Faouzi M, Zhang Z, Monteilh-Zoller M, Kelly Galbraith Kawabata F, Horgen D, Kawamori T, Penner R, Fleig A.
Inhibition of TRPM7 suppresses cell proliferation of colon adenocarcinoma in vitro and induces hypomagnesemia in vivo without affecting azoxymethane-induced early colon cancer in mice. Cell Commun Signal. 2017 Aug 15;15(1):30. doi: 10.1186/s12964-017-0187-9.PMED ID: 28810912.

New insights into Ca2+ channel function in health and disease

5/15/2017

 
Picture
Fleig A, Parekh AB.
​
New insights into Ca2+ channel function in health and disease. J Physiol. 2017 May 15;595(10):2997-2998. doi: 10.1113/JP274289.PMED ID: 28503825.

The coiled-coil domain of zebrafish TRPM7 regulates Mg·nucleotide sensitivity

9/15/2016

 
Picture
Jansen C, Sahni J, Suzuki S, Horgen FD, Penner R, Fleig A.
The coiled-coil domain of zebrafish TRPM7 regulates Mg·nucleotide sensitivity. Sci Rep. 2016 Sep 15;6:33459. doi: 10.1038/srep33459. PMED ID: 27628598.

Functional cooperation between KCa3.1 and TRPC1 channels in human breast cancer: Role in cell proliferation and patient prognosis

5/10/2016

 
Picture
Faouzi M, Hague F, Geerts D, Ay AS, Potier-Cartereau M, Ahidouch A, Ouadid-Ahidouch H.
Functional cooperation between KCa3.1 and TRPC1 channels in human breast cancer: Role in cell proliferation and patient prognosis. Oncotarget. 2016 May 10. doi: 10.18632/oncotarget.9261. PMED ID: 27183905.

Human CNNM2 is not a Mg(2+) transporter per se

4/11/2016

 
Picture
Sponder G, Mastrototaro L, Kurth K, Merolle L, Zhang Z, Abdulhanan N, Smorodchenko A, Wolf K, Fleig A, Penner R, Iotti S, Aschenbach JR, Vormann J, Kolisek M.
Human CNNM2 is not a Mg(2+) transporter per se. Pflugers Arch. 2016 Jul;468(7):1223-40. doi: 10.1007/s00424-016-1816-7. Epub 2016 Apr 11. PMED ID: 27068403.

TRPM7 kinase activity regulates murine mast cell degranulation

12/14/2015

 
Picture
Zierler S, Sumoza-Toledo A, Suzuki S, Ó Dúill F, Ryazanova LV, Penner R, Ryazanov AG, Fleig A.
TRPM7 kinase activity regulates murine mast cell degranulation. J Physiol. 2015 Dec 14. doi: 10.1113/JP271564. PMED ID: 26660477.

<<Previous

    Categories

    All

    Archives

    August 2018
    March 2018
    January 2018
    October 2017
    August 2017
    May 2017
    September 2016
    May 2016
    April 2016
    December 2015
    August 2015
    May 2015
    April 2015
    December 2014
    September 2014
    August 2014
    May 2014
    January 2014
    November 2013
    October 2013
    May 2013
    March 2013
    December 2012
    September 2011
    July 2011
    March 2011
    December 2010
    November 2010
    June 2010
    April 2010
    November 2009
    May 2009
    April 2009
    December 2008
    November 2008
    July 2008
    June 2008
    February 2008
    January 2008
    October 2007
    May 2007
    April 2007
    March 2007
    December 2006
    October 2006
    September 2006
    July 2006
    May 2006
    March 2006
    January 2006
    March 2005
    February 2005

04-28-2022


Telephone

+1-808-691-5366

Email

rpenner@hawaii.edu