More evidence emerges that TRPM7 modulates calcium signaling

Dr. Suzuki’s most recent publication in Cell Molecular Life Sciences further highlights the emerging picture of TRPM7’s regulatory participation in cellular calcium signaling. The study finds that TRPM7 kinase phosphorylation activity is required for orderly signaling downstream of Gq. This mechanism may support limiting GPCR-mediated calcium signaling in times of insufficient cellular ATP supply.